ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Paper COAs in 2026: It's Not Cheaper, It's Riskier

  Learn why sticking with paper records is a faulty strategy and discover how hidden costs, transcription errors, and regulatory red flags make digital COAs the only safe choice for modern trials.

• 7 eCOA Design Recommendations: Insights From Sites And CRAs

  Signant joined a group of C-Path members including other eCOA solution providers, sponsors, and regulators for a GBTI project that revealed several opportunities to improve eCOA usability and flexibility.

• Reliable Methods For Examining Long-Term Wearables In Gait & Sway

  Review this evaluation framework for wear duration when confirming if wearable sensor-based methods for capturing gait and balance impairment in the free-living environment are fit for purpose.

• Why Prioritizing Patients Changes How Study Teams Approach DHTs

  Participants are the number one contributing factor to the success of remote digital health technology. Consider these points when using DHTs to support patient-centered drug development.

• Clinical Trial Startup: Insights From The Industry

  Uncover key survey findings gleaned from the perspectives of over 500 clinical researchers regarding technological trends and recommendations for enhancing the overall site experience.

• AI‑Readiness Checklist: Is Your Clinical Data Environment Ready?

  AI impact depends on solid data practices, good governance, and team alignment. This piece highlights what to assess and how organizations can build readiness for future initiatives.

• What Are Decentralized Clinical Trials (DCTs)?

  Discover how DCTs leverage “virtual” tools, such as telemedicine, sensory-based technologies, wearable medical devices, and direct delivery of study drugs and materials to patients’ homes.

• Will DCTs Finally Democratize Clinical Trials?

  Who wouldn’t rather wear a smartwatch than drive 75 miles to have someone measure their blood pressure? See how DCTs have the capacity to include more people from a broader range of demographics.

• Optimizing Prader-Willi Syndrome Clinical Trials

  Learn how Signant is helping to mitigate placebo responses and ensuring high-quality data to improve Prader-Willi syndrome (PWS) clinical trial success.

• The Site-Sponsor Digital Divide Is Slowing Clinical Trial Innovation

  Clinical trial site digitization often stalls due to operational, cultural, and structural barriers. Site-centered workflows can overcome these, boosting efficiency, visibility, and execution.