ISPOR Top 10 HEOR Trends: What Are The Key Themes For 2026-27?

Artificial intelligence, real-world evidence, and value-based healthcare are redefining the future of health economics and outcomes research (HEOR). Drawing on input from 740 professionals across the global healthcare ecosystem, ISPOR’s latest Top 10 Trends report highlights the forces expected to shape evidence generation, market access, and healthcare decision-making through 2026 and 2027.

Key themes include the transition from AI experimentation to implementation, growing demand for transparent and accessible real-world data, evolving approaches to drug pricing and health technology assessment (HTA), and rising interest in measuring value beyond traditional clinical and economic outcomes. The discussion also explores how innovative therapies, patient-centric research, digital health technologies, and whole-health frameworks are challenging existing evaluation models and creating new expectations for HEOR professionals.

Discover how these trends are influencing healthcare systems worldwide and what organizations can do today to prepare for the next era of evidence-based decision-making.