Infographic | May 14, 2025

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Health Economics and Outcomes Research (HEOR) plays a vital role in guiding evidence-based decisions across the healthcare ecosystem. By integrating real-world evidence with clinical insights, HEOR supports informed decision-making for stakeholders including regulators, payers, providers, and patients. For regulators, HEOR fills gaps left by limited clinical trial data, especially in rare disease cases. Payers use HEOR to assess the health outcomes and economic impact of therapies, helping them determine whether treatments improve patient health while reducing broader healthcare system costs. Providers, such as physicians, apply HEOR findings to align treatment plans with individual patient goals, leading to more personalized care strategies. Patients, facing serious diagnoses, benefit from HEOR by gaining a clearer understanding of how different therapies might affect their quality of life and long-term outcomes.

In each case, HEOR enhances transparency, promotes cost-effective care, and improves treatment decisions by grounding them in real-world data. This multi-stakeholder application illustrates HEOR’s critical function in advancing value-based healthcare and optimizing patient outcomes across the continuum of care.

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ISPOR—The Professional Society for Health Economics and Outcomes Research