Digital Measurement Of Nocturnal Scratch In Atopic Dermatitis

A major challenge in managing atopic dermatitis (AD) is the lack of objective tools to measure the severity and impact of nocturnal scratching, a key symptom that disrupts sleep and worsens the skin barrier, leading to inflammation and infection. Traditional methods rely heavily on patient self-reporting and clinician observation, which are subjective and often unreliable. ActiGraph’s digital measurement solution addresses this gap by providing continuous, objective data on nighttime scratching and sleep quality through wearable sensors and machine-learning algorithms.

Clinically validated in individuals aged 2 to 75, this tool has shown strong correlation with established reference standards, including polysomnography and in-clinic video recordings. By integrating these digital measures with patient-reported outcomes, researchers can gain deeper insight into disease burden and therapeutic response. This approach supports more targeted interventions, enhances the drug development process, and may contribute to more robust evidence for regulatory approval. ActiGraph’s digital health technology platform is designed to support scalable, participant-friendly research in real-world settings.