Newsletter | September 17, 2026

09.17.26 -- AI, Wearables, And eTMF Are Exposing Trial Data Gaps

FEATURED EVENT: HEOR IS RESHAPING HEALTHCARE DECISIONS

ISPOR Europe 2026

In an era defined by rapid scientific advancement, fiscal pressures, evolving regulations, and growing expectations for equity and transparency, health economics and outcomes research (HEOR) provides the frameworks and insights needed to guide responsible and sustainable healthcare decision making. Thousands of global healthcare stakeholders will convene at ISPOR Europe 2026 to underscore the transformative role of HEOR in guiding better healthcare decisions.

EDITOR’S TAKE: WHY WEARABLE DATA FAILS BEFORE SOFTWARE

Why Wearable Trial Data Fails Before It Reaches Software

By John Oncea, Chief Editor, Clinical Tech Leader

An RF engineer explains why sensor physics and analog design determine whether wearable trial data is trustworthy long before software can analyze it.

AI, DATA TRUST, AND TRIAL TECHNOLOGY DECISIONS

AI’s Trial Bottleneck Moved To Operations, Not Models

By John Paul (JP) Lee, AG Mednet

AI has accelerated discovery, but clinical operations now create the bigger bottleneck. Learn why audit-ready data governance matters more than model speed.

Five eTMF Questions Sponsors Must Ask Before They Scale

By Florence Healthcare

The wrong eTMF platform creates manual oversight and inspection risk. Ask these five questions to support faster startup, site collaboration, and growth.

Why Vendor Selection Leverage Disappears Before Signing

By Kalyan Obalampalli, ClinAI

Your greatest leverage occurs before contracts are signed. Learn how to select flexible, long-term trial partners before negotiating power disappears.

How Sites Decide Which AI Tools Are Worth Adopting

By CRIO

Use a practical framework to assess vendor and homegrown AI tools, identify high-impact use cases, and make more informed implementation decisions.

Why eCOA And IRT Integration Is Becoming Essential

By Almac Clinical Technologies

Unified eCOA and IRT systems can reduce operational friction, improve data integrity, and create a better experience for patients and sites.

TOOLS FOR SMARTER STUDIES AND BETTER PATIENT EXPERIENCE

How Self-Driving Studies Could Change Trial Operations

Castor

What GLP-1 Studies Reveal About Trial Patient Experience

Medable

On-Demand HEOR Education For Better Evidence Decisions

ISPOR—The Professional Society for Health Economics and Outcomes Research