Newsletter | November 5, 2026

11.05.26 -- AI, Trial Planning, And Site Workflows Are Testing Readiness

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Global healthcare leaders will be convening in Denver, CO, in May 2027 for the premier conference for the health economics and outcomes research and healthcare communities around the world. With more than 100 countries represented, this is a unique opportunity to share new research, learn from peers and experts in the field, and drive advancements in healthcare decision making on a global scale. Registration is currently open at 2026 rates!

THE PLANNING AND TECHNOLOGY GAPS TRIALS CANNOT IGNORE

How AI Predicts Clinical Trial Performance Before Enrollment

By John Oncea, Chief Editor, Clinical Tech Leader

Explore how AI and early digital twin models can forecast trial performance, refine site feasibility, and anticipate operational needs before enrollment.

 

Two Clinical Planning Mistakes That Can Undermine Trials

By John Oncea, Chief Editor, Clinical Tech Leader

A veteran biostatistician explains how a critical planning document and a dose-selection shortcut can shape the success of clinical programs.

Four Stages Of Clinical Research Technology Maturity

By John Oncea, Chief Editor, Clinical Tech Leader

A 30-year clinical research veteran outlines four stages of technology maturity and explains why organizations often misjudge their own readiness.

AI, SITE WORKFLOWS, AND THE PRESSURE TO DELIVER

The Site AI Playbook: Choosing Tools That Fit Real Workflows

By CRIO

Compare vendor and homegrown AI options with a framework for identifying high-impact use cases, evaluating tools, and planning implementation.

Why Sponsors Are Taking Control Of Clinical Trial Builds

By Crucial Data Solutions

Building studies directly in EDC can accelerate startup and reduce rework. Explore how sponsor-led builds support flexibility and data quality.

How eCOA And Patient Payments Connect To Support Engagement

By Rajesh Puranik, Suvoda

See how automated micropayments linked to completed questionnaires support patient engagement and reduce manual payment work for site staff.

Why Trial Delays And Rising Costs Threaten U.S. Biotech

By Michelle Longmire, Medable

Michelle Longmire examines how startup delays, enrollment friction, disconnected systems, and rising costs undermine U.S. trial competitiveness.

How eCOA Helps Trial Teams Reduce Missing Patient Data

By Nathan Blubaugh, Almac Clinical Technologies

Digital assessments replace paper questionnaires to capture consistent, real-time participant data and help trial teams reduce missing entries.

TOOLS FOR TRIAL DOCUMENTATION AND DATA MANAGEMENT

Eliminate Paper Binders To Accelerate Trial Workflows

Florence Healthcare

A Clinical Data Platform For Medical Device Study Teams

Castor

ISPOR Partnerships In Health Economics And Outcomes Research

ISPOR—The Professional Society for Health Economics and Outcomes Research